The immune cytokine interleukin (IL)-7 and the β-chain of hepatocyte progress issue (HGF) mixture to type a naturally occurring heterodimer that stimulates the expansion of frequent lymphoid progenitors and immature B and T lymphoid cells. We’ve got cloned and expressed the heterodimer as a single-chain hybrid cytokine [recombinant (r) IL-7/HGFβ], which stimulates short-term hematopoietic stem…
