Oncolytic viruses are genetically engineered viruses designed for the remedy of stable tumors, and are sometimes coupled with the antitumor immunity of the host. The problem of utilizing oncolytic herpes simplex virus (oHSV) as an efficacious oncolytic agent is the potential host tissue harm attributable to the manufacturing of a variety of cytokines following intratumoral oHSV injection. An HSV‑suppressor of cytokine signaling 4 (SOCS4) recombinant virus was created to analyze whether or not it inhibits cytokine storm.
Recombinant HSV‑SOCS4 and HSV‑1(F) have been used to contaminate mice, and ranges of a number of consultant cytokines, together with monocyte chemoattractant protein‑1, interleukin (IL)‑1β, tumor necrosis issue‑α, IL‑6 and interferon γ, in serum and bronchoalveolar lavage fluid (BALF) of contaminated mice have been decided, and immune cells in BALF and spleen have been enumerated. Lung harm, virus titers within the lung, physique weight and survival charges of contaminated mice have been additionally decided and in contrast between the 2 teams.
The cytokine focus of HSV‑SOCS4‑contaminated mice was considerably decreased in contrast with that of HSV‑1(F)‑contaminated mice in BALF and serum, and a smaller variety of cluster of differentiation (CD)11b+ cells of BALF, and CD8+CD62L+ T cells and CD4+CD62L+ T cells of the spleen have been additionally recognized in HSV‑SOCS4‑contaminated mice. HSV‑SOCS4‑contaminated mice exhibited slight lung harm, a lower in physique weight reduction and a 100% survival price.
The outcomes of the current examine indicated that SOCS4 protein could also be a helpful regulator to inhibit cytokine overproduction, and that HSV‑SOCS4 could present a doable resolution to regulate cytokine storm and its penalties following induction by oncolytic virus remedy. On this examine, the antitumor exercise of the recombinant adenovirus KGHV500 was assessed with the MTT, TUNEL, Matrigel invasion and cell migration assays. To boost the intravenous supply of KGHV500 in vivo, cytokine-induced killer (CIK) cells have been used as a second vector to hold KGHV500. We explored whether or not CIK cells may carry the recombinant adenovirus KGHV500 containing the anti-p21Ras single chain fragment variable antibody (scFv) gene into tumors and improve antitumor efficiency.
A canine keratinocyte cell line expresses antimicrobial peptide and cytokine genes upon stimulation with micro organism, microbial ligands and recombinant cytokines.
Keratinocytes (KC) are the primary mobile elements of the stratum corneum that constitutes a stable bodily pores and skin barrier representing the primary line of protection towards pathogens. Furthermore, KC are potent producers of inflammatory mediators and antimicrobial peptides (AMP) when activated by way of their sample recognition receptors. In atopic dermatitis (AD) the protecting pores and skin barrier could also be compromised attributable to barrier disruption, secondary an infection and accelerated secretion of inflammatory cytokines which can additionally have an effect on AMP expression within the pores and skin. Within the current examine, we addressed the responses of a canine KC cell line upon publicity to Staphylococcus pseudintermedius, usually discovered on canine atopic pores and skin throughout secondary infections, and stimulation by particular person AD-associated ligands and cytokines.
All stimuli induced a major improve in expression of the pro-inflammatory cytokine genes tumor necrosis issue (TNF)-α and interleukin (IL)-8, however with totally different kinetics. Restricted results have been noticed on AMP gene expression aside from K9CATH which was considerably upregulated upon bacterial an infection however with not one of the particular person AD-associated ligands. Apparently, K9CATH possessed antimicrobial exercise in the direction of Staphylococcus pseudintermedius, indicating that K9CATH expression is a selected protection response in the direction of bacterial an infection and never a part of a basic pro-inflammatory profile of KC.
The Results of Mouse Recombinant Resistin on mRNA Expression of Proinflammatory and Anti-Inflammatory Cytokines and Warmth Shock Protein-70 in Experimental Stroke Mannequin.
Our current analysis confirmed that resistin has a neuroprotective impact towards stroke-induced damage by way of suppressing apoptosis and oxidative stress. Nevertheless, the molecular mechanism of neuroprotection of resistin is unclear. This work was designed to look at the impact of mouse recombinant resistin on mRNA expression of Tumor necrosis factor-α (TNF-α), Interleukin-1β (IL-1β), Interleukin-10 (IL-10), Reworking progress factor-β1 (TGF- β1), and Warmth shock protein-70 (HSP-70) in mouse mannequin of stroke.
Cytokines regulate nearly elements of innate and adaptive immunity, together with the initiation, execution and extinction of tumor-targeting immune responses. Over the previous three a long time, the opportunity of utilizing recombinant cytokines as a method to elicit or increase clinically related anticancer immune responses has attracted appreciable consideration. Nevertheless, solely three cytokines have been authorised up to now by the US Meals and Drug Administration and the European Medicines Company to be used in most cancers sufferers, specifically, recombinant interleukin (IL)-2 and two variants of recombinant interferon alpha 2 (IFN-α2a and IFN-α2b).
Canine Plasminogen ELISA Kit |
MBS738857-10x96StripWells |
MyBiosource |
10x96-Strip-Wells |
EUR 5685 |
Canine Plasminogen ELISA Kit |
MBS738857-48StripWells |
MyBiosource |
48-Strip-Wells |
EUR 485 |
Canine Plasminogen ELISA Kit |
MBS738857-5x96StripWells |
MyBiosource |
5x96-Strip-Wells |
EUR 3020 |
Canine Plasminogen ELISA Kit |
MBS738857-96StripWells |
MyBiosource |
96-Strip-Wells |
EUR 690 |
Canine Plasminogen ELISA Kit |
MBS762993-10x96StripWells |
MyBiosource |
10x96-Strip-Wells |
EUR 3900 |
Canine Plasminogen ELISA Kit |
MBS762993-48StripWells |
MyBiosource |
48-Strip-Wells |
EUR 340 |
Canine Plasminogen ELISA Kit |
MBS762993-5x96StripWells |
MyBiosource |
5x96-Strip-Wells |
EUR 2045 |
Canine Plasminogen ELISA Kit |
MBS762993-96StripWells |
MyBiosource |
96-Strip-Wells |
EUR 455 |
Canine Plasminogen (PLG) ELISA Kit |
EK8439 |
SAB |
96Т |
EUR 799 |
|
Canine Plasminogen (PLG) ELISA Kit |
AE26985DO-48Tests |
Abebio |
48 Tests |
EUR 360 |
|
Description: Canine (Canis familiaris; Dog) |
Canine Plasminogen (PLG) ELISA Kit |
AE26985DO-96Tests |
Abebio |
96 Tests |
EUR 680 |
|
Description: Canine (Canis familiaris; Dog) |
Canine Plasminogen(Plg) ELISA Kit |
NSL0809Ca |
Sunlong |
904 wells |
EUR 528 |
|
Canine Plasminogen (PLG) ELISA Kit |
RK07892 |
Abclonal |
96T |
EUR 280 |
Canine Plasminogen (PLG) ELISA Kit |
AE26985DO-48T |
Abebio |
48T |
EUR 360 |
|
Description: Canine (Canis familiaris; Dog) |
Canine Plasminogen (PLG) ELISA Kit |
AE26985DO-96T |
Abebio |
96T |
EUR 680 |
|
Description: Canine (Canis familiaris; Dog) |
Canine Plasminogen (Plg) ELISA Kit |
MBS2605356-10x96StripWells |
MyBiosource |
10x96-Strip-Wells |
EUR 3545 |
Canine Plasminogen (Plg) ELISA Kit |
MBS2605356-48StripWells |
MyBiosource |
48-Strip-Wells |
EUR 310 |
Canine Plasminogen (Plg) ELISA Kit |
MBS2605356-5x96StripWells |
MyBiosource |
5x96-Strip-Wells |
EUR 1940 |
Canine Plasminogen (Plg) ELISA Kit |
MBS2605356-96StripWells |
MyBiosource |
96-Strip-Wells |
EUR 475 |
Canine Plasminogen(Plg) ELISA Kit |
EIA06242Ca |
Enlibio |
each |
EUR 520 |
Canine PLG(Plasminogen) ELISA Kit |
ECA0018 |
FN Test |
96T |
EUR 681.12 |
|
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Canine;Sensitivity: 0.094 ng/ml |
Canine Plasminogen activator ELISA kit |
E01A68167 |
BlueGene |
96T |
EUR 700 |
Description: ELISA |
Canine Plasminogen Activator ELISA Kit |
MBS027296-10x96StripWells |
MyBiosource |
10x96-Strip-Wells |
EUR 6725 |
Canine Plasminogen Activator ELISA Kit |
MBS027296-48StripWells |
MyBiosource |
48-Strip-Wells |
EUR 550 |
Canine Plasminogen Activator ELISA Kit |
MBS027296-5x96StripWells |
MyBiosource |
5x96-Strip-Wells |
EUR 3420 |
Canine Plasminogen Activator ELISA Kit |
MBS027296-96StripWells |
MyBiosource |
96-Strip-Wells |
EUR 765 |
Canine Plasminogen activator ELISA Kit |
MBS751502-10x96StripWells |
MyBiosource |
10x96-Strip-Wells |
EUR 5685 |
Canine Plasminogen activator ELISA Kit |
MBS751502-48StripWells |
MyBiosource |
48-Strip-Wells |
EUR 485 |
Canine Plasminogen activator ELISA Kit |
MBS751502-5x96StripWells |
MyBiosource |
5x96-Strip-Wells |
EUR 3020 |
Canine Plasminogen activator ELISA Kit |
MBS751502-96StripWells |
MyBiosource |
96-Strip-Wells |
EUR 690 |
ELISA kit for Canine Plasminogen (PLG) |
KTE20045-48T |
Abbkine |
48T |
EUR 424.8 |
|
Description: Quantitative sandwich ELISA for measuring Canine Plasminogen (PLG) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids. |
ELISA kit for Canine Plasminogen (PLG) |
KTE20045-5platesof96wells |
Abbkine |
5 plates of 96 wells |
EUR 2702.4 |
|
Description: Quantitative sandwich ELISA for measuring Canine Plasminogen (PLG) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids. |
ELISA kit for Canine Plasminogen (PLG) |
KTE20045-96T |
Abbkine |
96T |
EUR 686.4 |
|
Description: Quantitative sandwich ELISA for measuring Canine Plasminogen (PLG) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids. |
Canine Plasminogen Activator, Tissue ELISA Kit |
MBS088023-10x96StripWells |
MyBiosource |
10x96-Strip-Wells |
EUR 6725 |
Canine Plasminogen Activator, Tissue ELISA Kit |
MBS088023-48StripWells |
MyBiosource |
48-Strip-Wells |
EUR 550 |
Canine Plasminogen Activator, Tissue ELISA Kit |
MBS088023-5x96StripWells |
MyBiosource |
5x96-Strip-Wells |
EUR 3420 |
Canine Plasminogen Activator, Tissue ELISA Kit |
MBS088023-96StripWells |
MyBiosource |
96-Strip-Wells |
EUR 765 |
Mouse plasminogen total antigen ELISA assay |
MBS480466-1Kit |
MyBiosource |
1Kit |
EUR 685 |
Mouse plasminogen total antigen ELISA assay |
MBS480466-5x1Kit |
MyBiosource |
5x1Kit |
EUR 3105 |
Human plasminogen total antigen ELISA assay |
MBS480467-1Kit |
MyBiosource |
1Kit |
EUR 580 |
Human plasminogen total antigen ELISA assay |
MBS480467-5x1Kit |
MyBiosource |
5x1Kit |
EUR 2610 |
Canine Plasminogen Activator Inhibitor 1 ELISA kit |
E01A67916 |
BlueGene |
96T |
EUR 700 |
Description: ELISA |
Canine Plasminogen Activator Inhibitor 2 ELISA kit |
E01A67942 |
BlueGene |
96T |
EUR 700 |
Description: ELISA |
Canine Plasminogen Activator Inhibitor 2 ELISA Kit |
MBS024905-10x96StripWells |
MyBiosource |
10x96-Strip-Wells |
EUR 6725 |
Canine Plasminogen Activator Inhibitor 2 ELISA Kit |
MBS024905-48StripWells |
MyBiosource |
48-Strip-Wells |
EUR 550 |
Canine Plasminogen Activator Inhibitor 2 ELISA Kit |
MBS024905-5x96StripWells |
MyBiosource |
5x96-Strip-Wells |
EUR 3420 |
Canine Plasminogen Activator Inhibitor 2 ELISA Kit |
MBS024905-96StripWells |
MyBiosource |
96-Strip-Wells |
EUR 765 |
Canine Plasminogen Activator Inhibitor 1 ELISA Kit |
MBS037967-10x96StripWells |
MyBiosource |
10x96-Strip-Wells |
EUR 6725 |
Canine Plasminogen Activator Inhibitor 1 ELISA Kit |
MBS037967-48StripWells |
MyBiosource |
48-Strip-Wells |
EUR 550 |
Canine Plasminogen Activator Inhibitor 1 ELISA Kit |
MBS037967-5x96StripWells |
MyBiosource |
5x96-Strip-Wells |
EUR 3420 |
Canine Plasminogen Activator Inhibitor 1 ELISA Kit |
MBS037967-96StripWells |
MyBiosource |
96-Strip-Wells |
EUR 765 |
Canine Plasminogen Activator Inhibitor 1 ELISA Kit |
MBS743848-10x96StripWells |
MyBiosource |
10x96-Strip-Wells |
EUR 5685 |
Canine Plasminogen Activator Inhibitor 1 ELISA Kit |
MBS743848-48StripWells |
MyBiosource |
48-Strip-Wells |
EUR 485 |
Canine Plasminogen Activator Inhibitor 1 ELISA Kit |
MBS743848-5x96StripWells |
MyBiosource |
5x96-Strip-Wells |
EUR 3020 |
Canine Plasminogen Activator Inhibitor 1 ELISA Kit |
MBS743848-96StripWells |
MyBiosource |
96-Strip-Wells |
EUR 690 |
Canine Plasminogen Activator Inhibitor 2 ELISA Kit |
MBS734435-10x96StripWells |
MyBiosource |
10x96-Strip-Wells |
EUR 5685 |
Canine Plasminogen Activator Inhibitor 2 ELISA Kit |
MBS734435-48StripWells |
MyBiosource |
48-Strip-Wells |
EUR 485 |
Canine Plasminogen Activator Inhibitor 2 ELISA Kit |
MBS734435-5x96StripWells |
MyBiosource |
5x96-Strip-Wells |
EUR 3020 |
Canine Plasminogen Activator Inhibitor 2 ELISA Kit |
MBS734435-96StripWells |
MyBiosource |
96-Strip-Wells |
EUR 690 |
Human plasminogen total antigen assay ELISA Kit |
MBS135487-1Kit |
MyBiosource |
1Kit |
EUR 490 |
Human plasminogen total antigen assay ELISA Kit |
MBS135487-5x1Kit |
MyBiosource |
5x1Kit |
EUR 2220 |
Mouse plasminogen total antigen assay ELISA Kit |
MBS135494-1Kit |
MyBiosource |
1Kit |
EUR 580 |
Mouse plasminogen total antigen assay ELISA Kit |
MBS135494-5x1Kit |
MyBiosource |
5x1Kit |
EUR 2630 |
Canine Urokinase plasminogen activator ELISA kit |
E01A69595 |
BlueGene |
96T |
EUR 700 |
Description: ELISA |
Canine Urokinase Plasminogen Activator ELISA Kit |
MBS020636-10x96StripWells |
MyBiosource |
10x96-Strip-Wells |
EUR 6725 |
Canine Urokinase Plasminogen Activator ELISA Kit |
MBS020636-48StripWells |
MyBiosource |
48-Strip-Wells |
EUR 550 |
Canine Urokinase Plasminogen Activator ELISA Kit |
MBS020636-5x96StripWells |
MyBiosource |
5x96-Strip-Wells |
EUR 3420 |
Canine Urokinase Plasminogen Activator ELISA Kit |
MBS020636-96StripWells |
MyBiosource |
96-Strip-Wells |
EUR 765 |
Canine Urokinase plasminogen activator ELISA Kit |
MBS736077-10x96StripWells |
MyBiosource |
10x96-Strip-Wells |
EUR 5685 |
Canine Urokinase plasminogen activator ELISA Kit |
MBS736077-48StripWells |
MyBiosource |
48-Strip-Wells |
EUR 485 |
Canine Urokinase plasminogen activator ELISA Kit |
MBS736077-5x96StripWells |
MyBiosource |
5x96-Strip-Wells |
EUR 3020 |
Canine Urokinase plasminogen activator ELISA Kit |
MBS736077-96StripWells |
MyBiosource |
96-Strip-Wells |
EUR 690 |
Canine Plasminogen Activator Inhibitor(PAI)ELISA Kit |
NSL1963Ca |
Sunlong |
2058 wells |
EUR 528 |
|
Canine Plasminogen Activator Inhibitor (PAI) ELISA Kit |
MBS2603087-10x96StripWells |
MyBiosource |
10x96-Strip-Wells |
EUR 3545 |
Canine Plasminogen Activator Inhibitor (PAI) ELISA Kit |
MBS2603087-48StripWells |
MyBiosource |
48-Strip-Wells |
EUR 310 |
Canine Plasminogen Activator Inhibitor (PAI) ELISA Kit |
MBS2603087-5x96StripWells |
MyBiosource |
5x96-Strip-Wells |
EUR 1940 |
Canine Plasminogen Activator Inhibitor (PAI) ELISA Kit |
MBS2603087-96StripWells |
MyBiosource |
96-Strip-Wells |
EUR 475 |
Canine Plasminogen Activator Inhibitor (PAI) ELISA Kit |
EIA06167Ca |
Enlibio |
each |
EUR 520 |
Canine Plasminogen Activator,Tissue(t-PA) ELISA Kit |
NSL0991Ca |
Sunlong |
1086 wells |
EUR 528 |
|
Canine Plasminogen Activator, Tissue (t-PA) ELISA Kit |
MBS2608321-10x96StripWells |
MyBiosource |
10x96-Strip-Wells |
EUR 3545 |
Canine Plasminogen Activator, Tissue (t-PA) ELISA Kit |
MBS2608321-48StripWells |
MyBiosource |
48-Strip-Wells |
EUR 310 |
Canine Plasminogen Activator, Tissue (t-PA) ELISA Kit |
MBS2608321-5x96StripWells |
MyBiosource |
5x96-Strip-Wells |
EUR 1940 |
Canine Plasminogen Activator, Tissue (t-PA) ELISA Kit |
MBS2608321-96StripWells |
MyBiosource |
96-Strip-Wells |
EUR 475 |
Canine Plasminogen Activator, Tissue (t-PA) ELISA KIT |
EIA06466Ca |
Enlibio |
each |
EUR 520 |
Canine Plasminogen-Related Protein B (PRPB) ELISA Kit |
MBS9393656-10x96StripWells |
MyBiosource |
10x96-Strip-Wells |
EUR 6725 |
Canine Plasminogen-Related Protein B (PRPB) ELISA Kit |
MBS9393656-48StripWells |
MyBiosource |
48-Strip-Wells |
EUR 550 |
Canine Plasminogen-Related Protein B (PRPB) ELISA Kit |
MBS9393656-5x96StripWells |
MyBiosource |
5x96-Strip-Wells |
EUR 3420 |
Canine Plasminogen-Related Protein B (PRPB) ELISA Kit |
MBS9393656-96StripWells |
MyBiosource |
96-Strip-Wells |
EUR 765 |
Canine Tissue type Plasminogen Activator ELISA kit |
E01A69178 |
BlueGene |
96T |
EUR 700 |
Description: ELISA |
Canine Tissue Type Plasminogen Activator ELISA Kit |
MBS015661-10x96StripWells |
MyBiosource |
10x96-Strip-Wells |
EUR 6725 |
Canine Tissue Type Plasminogen Activator ELISA Kit |
MBS015661-48StripWells |
MyBiosource |
48-Strip-Wells |
EUR 550 |
Canine Tissue Type Plasminogen Activator ELISA Kit |
MBS015661-5x96StripWells |
MyBiosource |
5x96-Strip-Wells |
EUR 3420 |
Canine Tissue Type Plasminogen Activator ELISA Kit |
MBS015661-96StripWells |
MyBiosource |
96-Strip-Wells |
EUR 765 |
Canine Tissue type Plasminogen Activator ELISA Kit |
MBS741760-10x96StripWells |
MyBiosource |
10x96-Strip-Wells |
EUR 5685 |
Canine Tissue type Plasminogen Activator ELISA Kit |
MBS741760-48StripWells |
MyBiosource |
48-Strip-Wells |
EUR 485 |
Canine Tissue type Plasminogen Activator ELISA Kit |
MBS741760-5x96StripWells |
MyBiosource |
5x96-Strip-Wells |
EUR 3020 |
Canine Tissue type Plasminogen Activator ELISA Kit |
MBS741760-96StripWells |
MyBiosource |
96-Strip-Wells |
EUR 690 |
*Canine Plasminogen Affinity Purified |
ICNPLGAP10MG |
Innovative research |
each |
EUR 3248 |
|
Description: *Canine Plasminogen Affinity Purified |
*Canine Plasminogen Affinity Purified |
ICNPLGAP1MG |
Innovative research |
each |
EUR 443 |
|
Description: *Canine Plasminogen Affinity Purified |
Canine Plasminogen Activator, Urokinase Receptor ELISA Kit |
MBS108772-10x96StripWells |
MyBiosource |
10x96-Strip-Wells |
EUR 6725 |
Canine Plasminogen Activator, Urokinase Receptor ELISA Kit |
MBS108772-48StripWells |
MyBiosource |
48-Strip-Wells |
EUR 550 |
Canine Plasminogen Activator, Urokinase Receptor ELISA Kit |
MBS108772-5x96StripWells |
MyBiosource |
5x96-Strip-Wells |
EUR 3420 |
Canine Plasminogen Activator, Urokinase Receptor ELISA Kit |
MBS108772-96StripWells |
MyBiosource |
96-Strip-Wells |
EUR 765 |
Canine Plasminogen Activator Inhibitor 1(PAI1)ELISA Kit |
NSL1964Ca |
Sunlong |
2059 wells |
EUR 528 |
|
Canine Plasminogen Activator Inhibitor 1 (PAI1) ELISA Kit |
MBS2603401-10x96StripWells |
MyBiosource |
10x96-Strip-Wells |
EUR 3545 |
Canine Plasminogen Activator Inhibitor 1 (PAI1) ELISA Kit |
MBS2603401-48StripWells |
MyBiosource |
48-Strip-Wells |
EUR 310 |
Canine Plasminogen Activator Inhibitor 1 (PAI1) ELISA Kit |
MBS2603401-5x96StripWells |
MyBiosource |
5x96-Strip-Wells |
EUR 1940 |
Canine Plasminogen Activator Inhibitor 1 (PAI1) ELISA Kit |
MBS2603401-96StripWells |
MyBiosource |
96-Strip-Wells |
EUR 475 |
Canine Plasminogen Activator Inhibitor 1 (PAI1) ELISA Kit |
EIA06168Ca |
Enlibio |
each |
EUR 520 |
Canine Urokinase Plasminogen Activator(uPA)ELISA Kit |
NSL2014Ca |
Sunlong |
2109 wells |
EUR 528 |
|
Canine urokinase plasminogen activator (uPA) ELISA Kit |
SL0041Ca |
Sunlong |
- |
EUR 528 |
|
Canine urokinase plasminogen activator (uPA) ELISA Kit |
MBS2603084-10x96StripWells |
MyBiosource |
10x96-Strip-Wells |
EUR 3545 |
Canine urokinase plasminogen activator (uPA) ELISA Kit |
MBS2603084-48StripWells |
MyBiosource |
48-Strip-Wells |
EUR 310 |
Canine urokinase plasminogen activator (uPA) ELISA Kit |
MBS2603084-5x96StripWells |
MyBiosource |
5x96-Strip-Wells |
EUR 1940 |
Canine urokinase plasminogen activator (uPA) ELISA Kit |
MBS2603084-96StripWells |
MyBiosource |
96-Strip-Wells |
EUR 475 |
Canine urokinase plasminogen activator(uPA)ELISA Kit |
EIA06499Ca |
Enlibio |
each |
EUR 520 |
Cyno monkey plasminogen total antigen assay ELISA kit |
MBS136009-1Kit |
MyBiosource |
1Kit |
EUR 615 |
Cyno monkey plasminogen total antigen assay ELISA kit |
MBS136009-5Kits |
MyBiosource |
5Kits |
EUR 2175 |
Cyno monkey plasminogen total antigen assay ELISA kit |
MBS136009-5x5Kits |
MyBiosource |
5x5Kits |
EUR 10060 |
Canine Plasminogen activator inhibitor 1,PAI-1 ELISA Kit |
YLA0044CA-48T |
Shanghai YL Biotech |
48T |
Ask for price |
Canine Plasminogen activator inhibitor 1,PAI-1 ELISA Kit |
YLA0044CA-96T |
Shanghai YL Biotech |
96T |
Ask for price |
Canine Plasminogen activator inhibitor 1, PAI-1 ELISA Kit |
MBS9305301-10x96StripWells |
MyBiosource |
10x96-Strip-Wells |
EUR 6725 |
Canine Plasminogen activator inhibitor 1, PAI-1 ELISA Kit |
MBS9305301-48StripWells |
MyBiosource |
48-Strip-Wells |
EUR 550 |
Canine Plasminogen activator inhibitor 1, PAI-1 ELISA Kit |
MBS9305301-5x96StripWells |
MyBiosource |
5x96-Strip-Wells |
EUR 3420 |
Canine Plasminogen activator inhibitor 1, PAI-1 ELISA Kit |
MBS9305301-96StripWells |
MyBiosource |
96-Strip-Wells |
EUR 765 |
Canine Plasminogen activator inhibitor 1, PAI-1 ELISA Kit |
MBS1609069-10x96StripWells |
MyBiosource |
10x96-Strip-Wells |
EUR 4295 |
Canine Plasminogen activator inhibitor 1, PAI-1 ELISA Kit |
MBS1609069-5x96StripWells |
MyBiosource |
5x96-Strip-Wells |
EUR 2185 |
Transient focal cerebral ischemia was induced by the center cerebral artery occlusion (MCAO) in mice. TNF-α, IL-1β, IL-10, TGF-β1, and HSP-70 mRNA have been detected at sham (zero hour), three hours, 6 hours, 12 hours, and 24 hours after MCAO utilizing real-time QRT-PCR methodology. Furthermore, animals have been handled with resistin on the dose of 400ng/mouse on the graduation of MCAO, and mRNA expression of the cytokines and HSP-70 was measured 24 hours after MCAO. Tumor necrosis factor-α and IL-1β mRNA expression markedly elevated at 12-hour time level after which returned to the basal degree at 24 hours after MCAO; however HSP-70 mRNA expression elevated at 24-hour time level. Moreover, resistin (400 ng/mouse) considerably elevated TGF-β1 and IL-10 and decreased HSP-70 gene expression at 24 hours after MCAO.